Artificial Intelligence and Computing in Medicine – Sano

Abstract Sano is a brand-new research institute dedicated to advancement of the use of computing in healthcare. The overall goal of Sano is to develop computerized solutions which can provide healthcare professionals and patients with assistance in making optimal medical and health-related decisions. The structure and the strategy towards achieving Sano’s goals is presented. I also discuss directions of healthcare research and areas of applications that Sano undertakes Author Arkadiusz Sitek Director of the Sano…

All-atom Markov Chain Monte Carlo simulation of protein folding and other large scale conformational changes

Abstract Many biologically relevant processes are characterized by major conformational changes of the involved biomolecules. While recent advances in experimental methods have improved our ability to observe proteins and other biomolecules these experiments do not give us a full account of the microscopic changes from which  the observable conformational changes arise. For a more complete…

Non-invasive diagnosis of pulmonary hypertension based on MRI images measurements and mathematical models’ interpretation

Abstract Pulmonary hypertension (PH) is a clinical condition characterised by an increased mean pulmonary arterial pressure measured, at rest, by right heart catheterisation (RHC). RHC is currently considered the gold standard for diagnosis, follow-up and measurement of response to treatment. Although the severe complications and mortality risk associated with the invasive procedure are reduced when…

Scientific computing at AstroCeNT

Abstract The talk will present the scientific activities of AstroCeNT and its Scientific Computing & Information Technology Group. AstroCeNT’s mission is to explore the hidden Universe. This mission is implemented by the development of tools needed for gravitational waves and dark matter detection. The AstroCeNT’s activities will be shown from the scientific computation perspective. During…

Multi-Component Lattice Boltzmann Equation simulation of blood from the cellular scale to the continuum scale

Abstract Lattice Boltzmann Equation (LBE) simulation method is a meso-scopic (distribution function-based) numerical technique, well adapted for computing certain classes of fluid flow, including complex multi-component flow, not least because of an intrinsic parallel implementability. Blood is a colloid, comprised of plasma (an incompressible Newtonian fluid) in which are suspended a high concentration of very…

Towards dynamic total-body metabolic and positronium imaging, Studies of positronium and microvesicles biomarkers

Abstract During the positron emission tomography about 40% of positrons annihilations occur through the creation of positronium (an atom composed of an electron from tissue and a positron emitted by a radioisotope). Positronium decays in the patient body are sensitive to the nanostructure and metabolism of the tissues. This phenomenon is not used in the…

The Communication System in Living Organism

Abstract The communication system is part of strategies employed by living organisms on a molecular level. The information storage and management is of high importance in keeping the steady state called homeostasis. The information consumption to achieve the required effect has been solved by evolution for random actions as well as for highly specific processes.…